Vol: 39 Page: 9

Authors:
Idzi Siatkowski
Joanna Zyprych-Walczak
Luiza Handschuh
Marek Figlerowicz

Title:
 The methods of normalization used in the analysis of two-color microarrays

Language: English

Keywords:
microarray cDNA
normalization
R software
bioconductor

Summary:
In this work the basic aspects of microarray data normalization are presented. Due to high level of complexity of microarray experiments their results are usually distorted. The normalization process allows to eliminate bias and to make comparison between distinct microarrays reliable. The main types of normalization of two-color microarray data are reviewed and presented using R and Bioconductor tools

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